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Good news for the millions of women who struggle with urinary tract infections (UTIs). The Food and Drug Administration (FDA) has approved a new drug, Blujepa, the first of a new class of oral antibiotics for treating UTIs, to head to market. Drugmaker GSK plans to release the drug in the U.S. in the second half of 2025. Blujepa, the brand name for gepotidacin, is the first oral antibiotic for UTIs to win FDA approval in almost 30 years. It’s approved for women and girls ages 12 and older with “uncomplicated UTIs,” which are often caused by bacteria including E. coli. The pill is part of U.K.-based pharmaceutical giant GSK’s pipeline of drugs fighting infectious diseases, and is being hailed as a breakthrough treatment as it comes at a time when bacteria are becoming increasingly resistant to the standard antibiotics. “The approval of Blujepa is a crucial milestone with UTIs among the most common infections in women,” Tony Wood, GSK’s chief scientific officer, said in a statement. According to GSK, 16 million women in the U.S. struggle with UTIs each year, and half of all women experience a UTI in their lifetime, with some 30% of women suffering from recurrent episodes. For many, UTIs can be a burden that severely impacts daily life,” said Dr. Thomas Hooton, professor of clinical medicine at the University of Miami School of Medicine. “With an increasing number of patients experiencing recurrent infections, there remains a clear need for continued research of antimicrobials to help address ongoing patient challenges and the strain on healthcare systems. Blujepa’s development was funded in part by the Department of Health and Human Services (HHS) and a number of other federal agencies, and comes at a time when the Trump administration is slashing the budgets and staff at the HHS and other key federal agencies. The HHS oversees 13 agencies, including the Centers for Disease Control and Prevention (CDC), which are tasked with protecting the nations health. Under new Health and Human Services Secretary Robert F. Kennedy Jr., hundreds of millions of dollars in grants for research have been cut, which critics say will hamper the country’s ability to make future breakthroughs in the medical field.
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For some people, home evokes feelings of joy and comfort. However, according to Ikeas new Life at Home Report, one in three people struggle to find the joy in their living spaces. The latest report explores why this isand how, in a world of uncertainty and constant change, small, simple adjustments can help bring more joy into everyday life. Insights gathered from more than 38,000 people across 39 countries show that, while many find it difficult to experience consistent enjoyment in their spaces, joy is often found in life’s smaller momentsthrough self-expression, cozy comforts, and playful touches. [Image: Ikea] The report highlights four key ingredients for joy at home: feeling good, having fun, building vibes, and making connections. The findings suggest that creating a joyful space doesnt require drastic changes. Often, its the small thingssuch as expressing personal style through décor, prioritizing well-being, or simply having funthat can make a difference. Its not about a total home makeover. Its about making small, meaningful changes that can really lift your everyday life, says Maria Jonsson, Global Insight Leader for the Ikea Life At Home Report. [Image: Ikea] Get organized The report found that one in three people say a tidy space boosts their overall well-being. When a space is clean and organized, a persons mind tends to feel clearer, Jonsson explains. Its not about perfection but creating a space that supports everyday well-being. Sleep was highlighted as the number-one activity for nurturing both physical and mental well-being at home. To improve sleep quality, Jonsson noted that it often comes down to getting the basics righta comfortable mattress, a cool, quiet room, and minimizing light and noise. Additionally, building a bedtime routine, such as limiting screen time before bed or maintaining a consistent sleep schedule, can enhance sleep hygiene at home. [Image: Ikea] Create a space for fun The report shows that 66% of people with homes that foster play consider their home their favorite place to be. Spaces that promote playfulness and creativity not only feel safer but also contribute to better mental well-being, with 42% of respondents reporting this benefit compared to the 38% global average. That might mean setting up a small, dedicated space for the things you lovelike a craft area, a reading corner, or a spot to do puzzles or play music. It doesnt have to be bigjust purposeful, Jonsson says. Creating distinct spaces at home for different activitiesand involving everyone in the design or decoration processcan help establish mental boundaries for starting new tasks, making the experience more enjoyable. By intentionally designing a home that encourages fun, it becomes easier to prioritize and make time for it, Jonsson emphasized. [Image: Ikea] Create a vibe Feeling a sense of belonging is essential to truly enjoying a home, the report found. Often, its the small, personal touches that make a space feel authenticwhether its a cherished object, a meaningful habit, or living in alignment with certain values and purpose. Enjoyment at home is experienced by 57% of people who feel a stronger sense of belonging when they can express their identity there. Homeownership is also linked to greater joy, with 55% of homeowners reporting joy compared to 47% of renters. However, according to the report, renter-friendly solutions trending on social media include peel-and-stick wallpaper, stick-on laminate flooring, temporary stained-glass-effect windows, and swapping out light fixtures or using budget-friendly uplights. Also trending in home design are dopamine decor, which involves designing spaces with colors, textures, patterns, and nostalgic elements, and biophilic design, which focuses on incorporating natural materials and elements to foster a calming atmosphere. [Image: Ikea] Foster connections The report found that gathering over food is a cherished activity for many. Those who see eating as a social experience are more likely to feel a sense of belonging and enjoyment at home. Creating more moments to eat together is a brilliant way to boost belonging and joy, Jonsson says. And globally, sitting down to a home-cooked meal ranks as one of the top five sources of joy. Additionally, people who find joy in laughing with others are more satisfied with their life at home (68% compared to the 61% global average). Designing spaces that foster conversation, connection, and shared experiences can significantly enhance how people feel in their homes. Personalization doesnt need to be expensive or complicatedits about surrounding yourself with things that tell your story. Whether thats family photos, art youve made, or souvenirs from travels, these details help your home feel like you, Jonsson says.
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Americas public lands, from its majestic national parks to its vast national forests, are at the heart of the countrys identity. They cover more than a quarter of the nation and large parts of the West. Some are crisscrossed by hiking trails and used by hunters and fishermen. Ranchers graze cattle on others. In many areas, the government earns money through oil, gas, timber and mining leases. These federally managed public lands have long enjoyed broad bipartisan support, as have moves to turn them into protected national parks and monuments. Research consistently shows that a majority of Americans want their congressional representatives to protect public access to these lands for recreation. One avenue for protection is the creation of national monuments. But the status of national monuments can change. Many of the United States national monuments, and much of its public land, are in the Western U.S. [Image: U.S. Geological Survey (USGS) Gap Analysis Project (GAP), 2024] Presidents have expanded and contracted national monuments, as the U.S. saw with Bears Ears National Monument in Utah over the course of the past three presidencies. The rules for the use and maintenance of various public lands can also change, and that can affect surrounding communities and their economies. The U.S. is likely to see changes to public lands again under the second Trump administration. One of the new administrations early orders was for the Department of Interior to review all national monuments for potential oil and gas drilling and mining. At least two national monuments that President Joe Biden created in California are among the new administrations targets. The avenue for many of these changes is rooted in one century-old law. The power and vagary of the Antiquities Act The Antiquities Act of 1906, signed into law by President Theodore Roosevelt, gave Congress or the president the authority to establish national monuments on federal land as a means of protecting areas for ecological, cultural, historical or scientific purposes. From Theodore Roosevelt on, 18 of the 21 presidents have used the Antiquities Act to create, expand or contract national monuments through a presidential proclamation. By using the Antiquities Act to create, expand or reduce national monuments, presidents can avoid an environmental impact statement, normally required under the National Environmental Policy Act, which also allows for public input. Supporters argue that forgoing the environmental impact statement helps expedite monument creation and expansion. Critics say bypassing the review means potential impacts of the monument designations can be overlooked. The Antiquities Act also offers no clarity on whether a president can reduce the amount of area protected by prior presidents. The act simply states that a president designates the smallest area compatible with the proper care and management of the objects to be protected. This has led to the shifting of national monument boundaries based on the priorities of each administration. The Citadel Ruins are the remains of Anasazi cliff dwellings at Bears Ears National Monument in Utah. [Photo: Bob Wick/Bureau of Land Management/Flickr] An example is Bears Ears, an area of Utah that is considered significant to several tribes but also has uranium, gas and oil resources. In 2016, President Barack Obama designated Bears Ears a national monument. In 2017, President Donald Trump signed a proclamation reducing Bears Ears by 80% of its total designated size. The monuments size and scope shifted a third time when President Joe Biden reestablished Bears Ears to the boundaries designated by Obama. In the span of just over five years, the monument was created, reduced, then restored to the original monument designation. The uncertainty about the long-term reliability of a designation makes it challenging for federal agencies to manage the land or assure Indigenous communities that the government will protect cultural, historical and ecological heritag. Public lands can be economic engines National parks and monuments can help fuel local economies. A 2017 study by Headwaters Economics, a nonprofit research group, found that Western rural counties with more public land have had greater economic growth, including in jobs and personal income, than those with little public land. National monuments can also benefit neighboring counties by increasing population, income and employment opportunities. Even small national monuments provide economic benefits for their surrounding communities. Visitors to Fort Stanwix National Monument in Rome, N.Y., spent $5.3 million in nearby communities in 2023, according to a National Park Service report. [Photo: National Park Service via Wikimedia Commons] While many counties adjacent to public lands may be dependent on natural resource extraction, the establishment of a national monument can open up new opportunities by expanding tourism and recreation. For example, four national parks and monuments in southeastern Utah, including Natural Bridges, drew about 2.4 million visitors who spent nearly US$400 million in surrounding communities. However, when there is uncertainty over whether public lands will remain protected, communities may be hesitant to invest in that future, not knowing whether it will soon change. What Congress and the courts could do There are a few ways to increase the certainty around the future of national monuments. First, lawsuits could push the courts to determine whether the president has the authority to reduce national monuments. Since the Antiquities Act doesnt directly address presidential authority to reduce monument size, thats an open question. Advocacy groups sued the government over Trumps authority to shrink Bears Ears National Monument, but their cases were put on hold after Biden expanded the monument again. The U.S. Supreme Court declined to hear other cases in 2024 that argued that a presidents authority to declare and expand national monuments should be far more limited under the law. Second, Congress could permanently protect designated national monuments through legislation. That would require presidential approval, and the process would likely be slow and cumbersome. Creating White Clouds Wilderness in Idaho, for example, took decades and a public campaign to have it designated a national monument before Congress approved its wilderness designation. Third, Congress could take new steps to protect public lands. For example, a bipartisan bill titled Public Lands in Public Hands Act could block privatization of public lands and increase and maintain access for recreation. One of the bills lead sponsors is U.S. Rep. Ryan Zinke, a Republican from Montana who served as Interior secretary during the first Trump administration. Whether the bill will pass and gain the presidents approval remains to be seen. Public lands have widespread support The Antiquities Act has led to the creation of 163 terrestrial and marine monuments and subsequently the protection of land and waters that hold cultural, scientific or historic significance. These monuments tend to have broad support. During the first Trump administration, there were over 650,000 public comments on Trumps review of national monument creation. An analysis found that 98% of the comments expressed broad support for both the creation and expansion of national monuments. Gold Butte National Monument covers nearly 300,000 acres of remote and rugged desert landscape in southeastern Nevada and is popular with hikers. [Photo: Bureau of Land Management] Public lands are more than just physical places. They are spaces where our ideals and values around public land unify us as Americans. They are quintessentially American and in many ways define and shape the American identity. Monica Hubbard is an associate professor of public policy and administration at Boise State University. Erika Allen Wolters is an assistant professor of political science at Oregon State University. This article is republished from The Conversation under a Creative Commons license. Read the original article.
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