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Days after hitting the market, the new pill version of Novo Nordisk’s wildly popular weight-loss drug will be available through Amazons online pharmacy. Amazon joins telehealth providers, discount prescription stalwart GoodRx, and even Novo Nordisk itself in providing the novel weight-management drug for consumers who want to pay out of pocket. With the introduction of the oral version of Wegovy, the weight-loss drugs that have taken the world by storm will become even more accessibleand more readily available for anyone who can pay out of pocket. The oral version of Wegovy will start at $149 a month out of pocket through Amazon Pharmacy, and will cost $25 a month with eligible insurance coverage. The 1.5-milligram and 4-milligram starter doses of Wegovy are priced at $149 per month, with the higher doses that many people move up to priced around $299. We know there are people who are interested in addressing their weight but have been waiting on the sidelines for a medicine that was right for them, Novo Nordisk marketing and patient solutions SVP Ed Cinca said in a press release. For many of them, that wait is over. Rivals race to market with a weight-loss pill The two companies that introduced the world to the GLP-1 diabetes and weight-loss drugs semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro and Zepbound) in injectionable form have been racing to market with a pill version of their hit drugs. Late last month, Novo Nordisk secured Food and Drug Administration (FDA) approval first, beating its rival drugmaker Eli Lilly, which expects its own drug to get the green light in March. The Danish drugmaker was also first to market with the injectable version of its weight-loss drug Wegovy, but it struggled on the production side when a massive wave of demand outstripped supply. That dynamic allowed Eli Lilly to gain ground with its own weight-management drug, Zepbound, and pushed the American drugmakers stock to new heights. In November, Novo Nordisk and Eli Lilly announced a deal with the Trump administration to make their upcoming weight-loss pills available for $149 out of pocket. Under the terms of the deal, part of the White Houses wider negotiation on drug prices, both companies will be exempt from tariffs on pharmaceutical products for three years. Beyond Amazon Pharmacy, Novos weight-loss pill will also be coming to TrumpRx, the Trump administrations upcoming portal that will connect consumers with drugmakers to lower prices. For many years, Americans have paid the highest prices anywhere in the world for prescription drugsmuch more than other countries for the exact same product, Trump said in a quote featured on the TrumpRx placeholder site. That ends today. TrumpRx is expected to launch in early 2026. Dr. Amazon will see you now If youre confused that Amazon is suddenly a healthcare provider, youre probably not alone. The company best known for its sprawling online storefront and ubiquitous delivery trucks jumped into the prescription drug business in 2020 when it launched its own online pharmacy, which grew out of a previous acquisition of a company called PillPack. In 2022, Amazon expanded its health ambitions by buying subscription-based primary care and telehealth provider One Medical for $3.9 billion. Last month, the tech giant launched a network of drug-vending kiosks, bringing its signature robotic touch to the pharmacy. The drug vending machines, located in some One Medical offices, are a no-footprint answer to major store closures from longtime drugstore companies like Walgreens, Rite Aid, and CVS. With widespread patient-initiated telehealth and cheaper weight-loss drugs popping out of vending machines, the future of medicine is, for better or worse, looking a lot more like the future in 2026.
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E-Commerce
As President Trump takes even more steps to pull back on climate action, Bill Gates is emphasizing how crucial government policies are crucial to addressing climate change. In his annual year-ahead letter, the billionaire Microsoft cofounder and philanthropist warns that the market alone is not enough to change our climate reality. Without a large global carbon tax (which is, unfortunately, politically unachievable), market forces do not properly incentivize the creation of technologies to reduce climate-related emissions, Gates writes. To stop global temperatures from increasing, we need to replace all emissions-emitting activities with affordable alternatives, Gates says. He particularly calls out industrial emissions and aviation as areas that need innovation. And government policiesin rich countries, he notesare crucial to bringing about that innovation, because unless innovations reach scale, the costs wont come down and we wont achieve the impact we need. Climate change is linked to poverty and health Gatess annual letter comes just a few months after he wrote a blog arguing that the world is too focused on cutting short-term emissions, and that focusing on climate change risks getting in the way of addressing global poverty. That post sparked some backlash from environmental activists and experts who noted that climate and development goals are interconnected. If you look around the world right now, climate change is directly undermining human development goals, poverty eradication, and health goals, Rachel Cleetus, senior policy director for the climate and energy program at the Union of Concerned Scientists, told Fast Company back in October. In his annual letter, Gates said that, If we dont limit climate change, it will join poverty and infectious disease in causing enormous suffering, especially for the worlds poorest people. Climate change will also worsen both those hardships: Experts have long said that climate change exacerbates disease outbreaks and pandemics, and that it is expected to push up to 132 million people into extreme poverty by 2030. ‘Investing more than ever to climate work’ In his October post, Gates said that although climate change will hurt poor people more than anyone else, the biggest problems to poor people are poverty and disease. Understanding this, he wrote, will let us focus our limited resources on interventions that will have the greatest impact for the most vulnerable people. In his year-ahead letter, though, Gates emphasized climate change as a critical area for the world to focus on. He added that he will be investing and giving more than ever to climate work in the years ahead while also continuing to give more to childrens health. Some of his investments around climate change will use AI. His foundation has committed $1.4 billion to helping farmers adapt to climate extremes, and in his annual letter, he says that with AI, we will soon be able to provide poor farmers with better advice about weather, prices, crop diseases, and soil than even the richest farmers get today. How Trump has devastated climate action The Trump administration has taken multiple steps to inhibit America’s climate progress. Most recently, Trump pulled the country out of a a landmark climate treaty, the U.N. Framework Convention on Climate Change. Trump has also canceled billions in green energy projects, rolled back Biden-era government incentives for clean technologies, and cut hundreds of millions of dollars from climate and renewable energy research. At the same time, Trump has rapidly increased the governments support of greenhouse gas-emitting fossil fuels, opening new mining leases, loosening coal plant emissions standards, and forcing coal plants that were going to close to keep operating. Trumps actions have devastated multiple climate companies. Even Gatess own climate actions faced a challenging 2025: In March, Breakthrough Energy, a climate group Gates started 10 years ago, laid off dozens in its U.S. and Europe policy teams. But Gates will continue to put billions into climate innovation, he writeswhile also focusing on health and education. And all three of those areas, he notes, can improve rapidly with the right government focus.
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E-Commerce
General Motors will be hit with charges of about $6 billion as sales of electric vehicles sputter after the U.S. cut tax incentives to buy them and also eased auto emissions standards. Shares slid almost 3% Friday. The charges that will be recorded in the fourth quarter follow an announcement in October that the Detroit automaker would take a $1.6 billion charge for the same reason in the previous quarter, with automakers forced to reconsider ambitious plans to convert their fleets to electric power. The EV tax credit ended in September. The clean vehicle tax credit was worth $7,500 for new EVs and up to $4,000 for used ones. GM, which had been the most ambitious among all U.S. automakers with plans to replace internal combustion engines, said in its filing with the Securities and Exchange Commission late Thursday that the $6 billion in charges includes non-cash impairments and other non-cash charges of about $1.8 billion as well as supplier commercial settlements, contract cancellation fees, and other charges of approximately $4.2 billion. EVs have been considered to be the future of the US automotive industry. GM announced in 2020 that it was going to invest $27 billion in electric and autonomous vehicles over the next five years, a 35% increase over plans made before the pandemic. GM expected more than half of its factories in North America and China would be capable of making electric vehicles by 2030. It also pledged at the time to increase its investment in EV charging networks by nearly $750 million through 2025. Its goal was to make the vast majority of the vehicles electric by 2035, and the entire company carbon neutral five years after that. Those plans have been shaken due to the drastic differences in economic and environmental policies between the Biden and Trump administrations. China has become a global leader in electric vehicle technology in recent years, with factories there churning out millions of cars and laying the groundwork for a massive charging network for vehicles. Earlier this month, Tesla was dethroned as the world’s largest EV automaker, replaced by China’s BYD, which produced 2.26 million electric vehicles last year. Michelle Chapman, AP business writer
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E-Commerce
Sluggish December hiring concluded a year of weak employment gains that have frustrated job seekers even though layoffs and unemployment remained low. Employers added just 50,000 jobs last month, nearly unchanged from a downwardly revised figure of 56,000 in November, the Labor Department said Friday. The unemployment rate slipped to 4.4%, its first decline since June, from 4.5% in November, a figure also revised lower. The data suggests a reluctance by businesses to add workers even as economic growth has picked up. Many companies hired aggressively after the pandemic and no longer need to fill more jobs. Others have held back due to widespread uncertainty caused by President Donald Trumps shifting tariff policies, elevated inflation, and the spread of artificial intelligence, which could alter or even replace some jobs. Still, economists were encouraged by the lower unemployment rate, which had risen in the previous four straight reports. Weakening employment raised alarms at the Federal Reserve, which cut its key interest rate three times last year. The labor market looks to have stabilized, but at a slower pace of employment growth, Blerina Uruci, chief economist at T. Rowe Price, said. “There is no urgency for the Fed to cut rates further, for now.” Some Federal Reserve officials are concerned that inflation hasn’t improved since 2024 and remains above their target of 2% annual growth. They support keeping rates where they are to combat inflation. Others, however, have grown worried that hiring has nearly ground to a halt and have supported lowering borrowing costs to spur spending and growth. November’s job gain was revised slightly lower, from 64,000 to 56,000, while October’s now shows a much steeper drop, with a loss of 173,000 positions, down from previous estimates of a 105,000 decline. The government revises the jobs figures as it receives more survey responses from businesses. Nearly all the jobs added in December were in the health care and restaurant and hotel industries. Health care added 38,500 jobs, while restaurants and hotels gained 47,000. Governments mostly at the state and local level added 13,000. Manufacturing, construction and retail companies all shed jobs. Retailers cut 25,000 positions, a sign that holiday hiring has been weaker than previous years. Manufacturers have shed jobs every month since April, when Trump announced sweeping tariffs intended to boost manufacturing. Wall Street and Washington are looking closely at Friday’s report as it’s the first clean reading on the labor market in three months. The government didnt issue a report in October because of the six-week government shutdown, and Novembers data was distorted by the closure, which lasted until Nov. 12. Job gains have been subdued all year, particularly after Aprils liberation day tariff announcement by Trump. The economy gained just 584,000 jobs in 2025, sharply lower than that more than 2 million added in 2024. Its the smallest annual gain since the COVID-19 pandemic decimated the job market in 2020. Outside of recessions, it’s the smallest annual increase since 2003. Still, Trump boasted on social media late Thursday that since January, all the new jobs have been in the private sector, while government jobs have declined. Yet his figures included December’s jobs numbers as well as revisions to previous months, which the White House receives Thursday afternoon, before the figures are publicly released. Trump’s post on Truth Social said that 654,000 jobs were added by businesses since January, while government jobs declined 181,000, so it wouldn’t have been immediately clear that the post had new information from December. But new jobs data are generally closely guarded since they can move financial markets. The hiring slowdown reflects more than just a reluctance by companies to add jobs. With an aging population and a sharp drop in immigration, the economy doesn’t need to create as many jobs as it has in the past to keep the unemployment rate steady. As a result, a gain of 50,000 jobs is not as clear a sign of weakness as it would have been in previous years. And layoffs are still low, a sign firms aren’t rapidly cutting jobs, as typically happens in a recession. The low-hire, low-fire job market does mean workers have some job security, though it’s become harder to find new work. Ernesto Castro, 44, has applied for hundreds of jobs since leaving his last in May. Yet the Los Angeles resident has had just three initial interviews, and only one follow-up, after which he heard nothing. With nearly a decade of experience providing customer support for software companies, Castro expected to find a new job pretty quickly as in the past. Its been awful, he said. He worries that more companies are turning to artificial intelligence to help clients learn to use new software. He hears ads from tech companies that urge companies to slash workers like him in favor of AI. His contacts in the industry say that employees are increasingly reluctant to switch jobs amid all the uncertainty, which means fewer open jobs for others. He is now looking into starting his own software company, and is also exploring project management roles. Subdued hiring underscores a key conundrum surrounding the economy as it enters 2026: Growth has picked up to healthy levels, yet hiring has weakened noticeably. Most economists expect hiring will accelerate this year amid solid growth, and Trump’s tax cut legislation is expected to produce large tax refunds this spring. Yet economists acknowledge there are other possibilities: Weak job gains could drag down future growth. Or the economy could keep expanding at a healthy clip, while automation and the spread of artificial intelligence reduces the need for more jobs.
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E-Commerce
U.S. stocks are rising toward records Friday following a mixed report on the U.S. job market, one that may delay another cut to interest rates by the Federal Reserve but does not slam the door on it. The S&P 500 climbed 0.5% in midday trading and was on track to top its all-time high set earlier in the week. The Dow Jones Industrial Average added 237 points, or 0.5% and was also heading toward a record. The Nasdaq composite was 0.7% higher, as of 11:45 a.m. Eastern time. The gains came after the U.S. Labor Department said employers hired fewer workers in total during December than economists expected, though the unemployment rate improved and was better than expected. It reinforced how the U.S. job market may be in a low-hire, low-fire state. On Wall Street, power company Vistra soared 11.9% to lead the market after signing a 20-year deal to provide electricity to Meta Platforms from three of its nuclear plants. Big Tech companies have been signing a string of such deals to electrify the data centers powering their moves into artificial-intelligence technology. Oklo jumped 12.3% after saying it also signed a deal with Meta Platforms that will help it secure nuclear fuel and advance its project to build a facility in Pike County, Ohio. Homebuilders and other companies involved in the housing market were also strong in their first trading after President Donald Trump announced a plan to lower mortgage rates. Trump on late Thursday called for the purchase of $200 billion in mortgage bonds, similar to how the Fed in the past has bought bonds backed by mortgages to bring down mortgage rates. Builders FirstSource, a supplier of building products, jumped 8.5% for one of the biggest gains in the S&P 500 after Vistra. Among homebuilders, Lennar rose 5.1%, PulteGroup rose 4.9% and D.R. Horton climbed 4.8%. They helped offset a 3.3% drop for General Motors. The auto giant said it will take a $6 billion hit to its results for the last three months of 2025 related to its pullback from electric vehicles. Thats on top of the $1.6 billion in charges GM took in the prior quarter. Fewer tax incentives and easier fuel-emission regulations have been eating into demand for EVs. WD-40 tumbled 5% after reporting a weaker profit for the latest quarter than analysts expected. Chief Financial Officer Sara Hyzer said the soft numbers were primarily because of timing issues, not weaker demand from end customers, and the company stood by its financial forecasts for the upcoming year. In the bond market, Treasury yields were mixed following the mixed jobs report. The improvement in the unemployment rate was enough to get traders to ratchet back expectations for a cut to interest rates at the Feds next meeting, which is scheduled for later this month. Traders are now forecasting just a 5% chance of that, down from 11% a day before, according to data from CME Group. But traders nevertheless still largely expect the Fed to cut rates at least twice this upcoming year. Whether theyre correct carries high stakes for financial markets. Lower interest rates can goose the economy and push up prices for investments, though they can also worsen inflation at the same time. And inflation has stubbornly remained above the Feds 2% target. Until the data provide a clearer direction, a divided Fed is likely to stay that way, according to Ellen Zentner, chief economic strategist for Morgan Stanley Wealth Management. Lower rates are likely coming this year, but the markets may have to be patient. The yield on the 10-year Treasury eased to 4.17% from 4.19% late Thursday. It tends to track expectations for longer-term economic growth and inflation. The two-year Treasury yield, which more closely tracks forecasts for what the Fed will do with short-term interest rates in the near term, rose to 3.52% from 3.49%. A separate report released Friday morning suggested sentiment among U.S. consumers is strengthening, particularly among lower-income households. Perhaps more importantly for the Fed, the preliminary report from the University of Michigan also said expectations for inflation in the coming 12 months may be at their lowest level in a year. That could prevent a vicious cycle where worsening expectations lead to behaviors that accelerate inflation further. In stock markets abroad, indexes rose across much of Europe and Asia. The French CAC 40 rose 1.3%, and Japans Nikkei 225 jumped 1.6% for two of the worlds bigger gains. In Tokyo, Fast Retailing, the fashion company behind Uniqlo, jumped 10.7% after its quarterly operating profit surged about 34% year-on-year. It revised its full-year forecasts upward. By Stan Choe, AP business writer AP Business Writers Chan Ho-him and Matt Ott contributed.
Category:
E-Commerce
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